In conclusion - natural products can be considered as promising drugs for anti-atherosclerotic therapy. Two-year treatment with allicor has a direct anti-atherosclerotic effect on carotid atherosclerosis in asymptomatic men. Inflaminat possessing anti-cytokine activity caused regression of carotid atherosclerosis as a result of 1-year treatment of asymptomatic men. Phytoestrogen-rich drug karinat prevented development of carotid atherosclerosis in postmenopausal women.