Earlier (Orekhov AN et al. CurrPharm Des 2018; 24 (26): 3143-3151), studying the mechanisms of accumulation of intracellular cholesterol, we identified key genes (master regulators) associated with the accumulation of cholesterol but at the same time actively participating in the pro-inflammatory response. This slide shows which signaling pathways identified in this work may be associated with the master regulators of the pro-inflammatory response identified earlier.