РусскийEnglish (UK)
     
 

Orekhov AN, Bobryshev YV, Chistiakov DA.

Cardiovasc Res. 2014 Jul 11. pii: cvu168. [Epub ahead of print]

Abstract

Pericytes which are also known as Rouget cells or perivascular cells are considered to represent a likely distinct pool of vascular cells that are extremely branched and located mostly in the periphery of the vascular system. The family of pericytes is a heterogeneous cell population that includes pericytes and pericyte-like cells. Accumulated data indicates that networks of pericyte-like cells exist in normal non-atherosclerotic intima and that pericyte-like cells can be involved in the development of atherosclerotic lesions from the very early stages of disease. The pathogenic role of arterial pericytes and pericyte-like cells also might be important in advanced and complicated atherosclerotic lesions via realizing mechanisms of vascular remodeling, ectopic ossification, intraplaque neovascularization, and probably thrombosis.

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: This email address is being protected from spambots. You need JavaScript enabled to view it. .

KEYWORDS: arteries; atherogenesis; atherosclerosis; blood vessels; intima; pericyte-like cells; pericytes