Gorieva ShB, Kameneva AM, Iurenev AP, Orekhov AN
Kardiologiia 1992 Jan 32:1 11-3
The study was undertaken to examine 190 males, aged 30-60 years who were divided into 4 groups: (1) patients with essential hypertension; (2) those with postinfarction cardiosclerosis; (3) those with postinfarction cardiosclerosis and essential hypertension; (4) healthy individuals. The levels of apolipoproteins B and A1 and circulating immune complex cholesterol were examined in the cold (winter) and hot (summer) seasons in the areas of arid (Ashkhabad) and temperate (Moscow) climate. The major apo-proteins were determined by enzyme uncompetitive immunoassay. Cholesterol levels in the immune complexes were measured by the method developed at the Institute of Experimental Cardiology, All-Union Cardiology Research Center, USSR Academy of Medical Sciences. The Moscow examinees were found to have more profound changes in the lipid spectrum than the Ashkhabad ones. In both climatic zones, the level of the major apo-proteins and their ratio were unaffected by seasonal variations.