In this presentation i will talk about atherogenic potential of patients’ blood or atherogenicity. We have discovered this phenomenon using primary culture of cells isolated from human aorta. I think it is necessary to describe cells we used and to give our ideas on cellular mechanisms of atherosclerosis, especially on lipidosis that is lipid accumulation in arterial cells. Then i would like to explain the phenomenon of atherogenicity and our attempts to apply the knowledge on atherogenicity into clinical practice.